When you think of tobacco, your mind may instinctively take you back to an old ‘80s Holden Commodore, windows down, fabric interiors etched with the scent of Winfield Blues…
But thankfully, we’re not talking about that kind of tobacco.
The star of our Phyto-A+ Australian Native Tobacco Serum is Nicotiana benthamiana, a wild Australian plant that does belong to the tobacco family—yes—but what we’ve harnessed from it is far from cigarettes and smoky lounges.
Instead, this humble flowering plant is the botanical host for Reneseed™, a breakthrough biotechnological active that’s designed to help support collagen production and skin renewal in a way that’s gentle, plant-powered and backed by emerging science.
From outback flower to biotech superstar
Nicotiana benthamiana has been used by Indigenous Australians for generations and studied in science labs around the world. Why? Because this humble plant is incredibly good at producing complex proteins, including one very special one that supports healthy, youthful-looking skin.
Through a natural (and non-GMO) process called transient expression, scientists introduce a synthetic gene into the plant’s leaves. The plant then does its thing, producing a purified peptide called Hexapeptide-40 sh-polypeptide-76. That’s the active ingredient in Reneseed™, and it’s the collagen-supporting powerhouse behind our Phyto-A+ Serum.
Think of the plant like a mini lab in the soil, growing the good stuff, minus the chemicals or harsh processing.
As Dr Annie Holden, anthropologist and founder of Founder’s Formula, explains: “Reneseed is one of the most exciting ingredients we’ve worked with. It gives us a way to support skin structure and vitality using Australian nature and clean, scientific precision. It’s gentle, potent and proudly plant-based.”
What does Reneseed™ do?
Reneseed™ has been clinically tested by its developer, and the results are seriously impressive:
- Helps support collagen I production
- Helps improve epidermal thickness and lipid synthesis (hello, plumpness)
- Helps reduce the appearance of fine lines and visible pores
- Helps boost firmness, elasticity and hydration
And, unlike retinol, it does all that without the irritation or sun sensitivity.
In fact, in clinical studies, Reneseed™ was shown to be 4x more effective than retinol at stimulating collagen.
Real results from real people
When tested in a 28-day study on women aged 45–65 using 2% Reneseed™, researchers found:
- Up to 42% reduction in wrinkle count
- Up to 28% boost in hydration
- Up to 22% increase in firmness
- Visible improvement in radiance and texture
All without the redness, peeling or flaking that often comes with traditional active ingredients.
It’s important to add that individual results may vary and we always recommend consulting a healthcare professional before starting a new skincare regimen.
Why call it ‘Native Tobacco Serum’?
We get this question a lot, and it’s a good one. While the serum isn’t made from tobacco, the name pays homage to its source plant, Nicotiana benthamiana. It’s a uniquely Australian story: combining ancient botanicals with cutting-edge biotechnology to support skin health, naturally.
Who is the Phyto-A+ Australian Native Tobacco Serum for?
Our serum is for anyone looking to support their skin through natural, science-backed means. It’s suitable for most skin types and may be especially beneficial for those noticing signs of environmental or age-related skin changes. And thanks to its gentle formulation, it’s ideal for daytime use, something traditional retinoids can’t always claim. Always patch test before use. If you have specific skin concerns, we recommend speaking with your healthcare provider.
Use morning or night, before moisturiser, and follow with your favourite SPF during the day.
Award-winning innovation, recognised globally
Our Phyto-A+ Australian Native Tobacco Serum was recently named Editor’s Choice at the prestigious international Beauty Shortlist Awards.
Celebrated for its plant-powered innovation and performance, our serum has been recognised as one of the most advanced biotechnological serums available today.
It’s one more reason we’re so passionate about combining native Australian ingredients with leading-edge science, and it makes our Gift Set perfect for anyone looking to start their Australian botanical skincare journey.
Proof that plants are powerful
At Founder’s Formula, we believe skincare should work in harmony with nature and your skin. The Phyto-A+ Australian Native Tobacco Serum is our way of celebrating both. Powered by Reneseed™, supported by science and inspired by Australian biodiversity, it’s a serum designed to do more with less.
Experience the award-winning difference and shop our winning formulas today.
Curious about more plant-powered skincare?
Take a look at the benefits of Kakadu Plum or get the latest facts in our Vitamin C myth-buster.